Description
AROFAST-GOLD 20 is a stronger form of the triple-action heart protector capsule by Arrowin Pharmaceuticals containing Atorvastatin (20 mg), Aspirin (75 mg), and Clopidogrel Sulphate (75 mg). This drug is meant for people who need more lipid-lowering power along with antiplatelet combination therapy, usually because they have high levels of risk for their hearts or high baseline cholesterol that needs to be lowered beyond the capability of the 10 mg form of Atorvastatin. Like the other version, this one provides the patient a single capsule that tackles both cholesterol and blood clot prevention.
How Atorvastatin 20 mg, Aspirin 75 mg, and Clopidogrel Sulphate 75 mg Capsules Work
Atorvastatin in the higher dose of 20 mg reduces LDL (or “bad” cholesterol) more effectively by blocking the enzyme HMG-CoA reductase that is responsible for the production of cholesterol in the liver and slows down the formation of atherosclerotic plaques in arteries. Aspirin blocks the enzyme COX-1 and decreases the synthesis of thromboxane A2, thus inhibiting platelet aggregation. Clopidogrel sulphate blocks the platelet receptor P2Y12 by another pathway and increases the antiplatelet effect. Therefore, this three-drug combination ensures not only better lipid control but also a dual antiplatelet effect.
Uses / Indications
- Secondary Prevention of Heart Attack and Stroke in Patients with Increased Cardiovascular Risk
- Follow-up care after stenting or bypass surgery that demands dual antiplatelet treatment along with statins
- Patients who have increased baseline LDL cholesterol levels needing more intensive lipid reduction medications
- Heart disease and acute coronary syndrome, managed by cardiologists
- Maintenance medication for cardiac patients with higher risks, who need single capsule medication
Dosage & Administration
It is recommended that AROFAST-GOLD 20 be taken in doses of one capsule per day, ideally at the same time every day, whether with meals or not, and as directed by the physician in charge. The tablet must be taken whole, along with water. Since the dosage of the statin drug is much higher and because the combination includes an antiplatelet mechanism, the treatment must be initiated by a physician or cardiologist.
Side Effects
Patients on this higher-strength triple combination should be aware of the following possible effects:
- Increased risk of bleeding or bruising, including gastrointestinal bleeding
- Muscle pain or weakness (myalgia), which may be more noticeable at the higher statin dose
- Nausea or stomach upset
- Headache
- Dizziness
- Indigestion or heartburn
- Elevated liver enzymes
Signs of unusual bleeding, black or tarry stools, prolonged bleeding from cuts, unexplained muscle pain accompanied by fever, or dark urine should be reported to a doctor immediately.
Precautions & Warnings
- Indicated for use solely under the direction of a cardiologist/physician by prescription
- Contraindicated for use in patients with active bleeding, bleeding problems, or a history of hemorrhagic stroke
- Patients with active liver disease or with persistent elevation of liver enzymes not explained should avoid use
- Pregnancy and lactation are contraindicated
- Should be avoided in patients with a history of peptic ulcers or gastrointestinal bleeding
- Used cautiously before surgery and dental procedures because of increased bleeding tendency
- It should not be stopped abruptly, especially in the presence of coronary stents, without the advice of the cardiologist due to increased risk of clot formation
- Monitoring of liver function, lipids, and blood counts is advised in long-term treatment
- Limit alcohol intake because of possible increased risks of adverse effects on the gastrointestinal tract and liver, especially with the high dose of the statin
Drug Interactions
AROFAST-GOLD 20 could have interactions with anticoagulants, NSAIDs, proton-pump inhibitors (especially Omeprazole, which may decrease the effectiveness of Clopidogrel), other cholesterol-lowering medications, and medications that affect bleeding and liver metabolism. A full list of medicines that the patient is using must always be consulted by the physician prescribing the drug.
Storage
Store below 25°C in a cool, dry place, away from direct sunlight and moisture. Keep out of reach of children.
PCD Pharma Franchise Opportunity for Atorvastatin 20 mg, Aspirin 75 mg, and Clopidogrel Sulphate 75 mg Capsules
With increased demand for high-strength statins along with dual antiplatelets among cardiac patients, the AROFAST-GOLD 20 provides franchise partners with the benefit of having a unique and physician-preferred combination that caters to higher cardiovascular risk patients. Along with the 10mg version, it allows partners the advantage of having all strength versions of the triple combination cardioprotective brand in one single brand.
AROFAST-GOLD 20 is marketed by Arrowin Pharmaceuticals under its renowned Medace (Cardiac-Diabetic) division, adhering to the WHO-GMP manufacturing norms and providing partners with affordable pricing and complete marketing assistance at no extra cost, including visuals, product glossaries, and LBLs. Business partners get district-wise monopoly rights under the Pan-India Monopoly Model of Arrowin Pharmaceuticals, which ensures exclusivity for franchise partners by providing them with consistent and reliable supply without any competition internally to the brand.
Franchise in AROFAST-GOLD 20 can be availed by chemists, stockists, and franchise partners who have a valid Drug License (Form 20/21) for a cardiac-diabetic product basket.
