Description
Temgrip-650 | Paracetamol 650mg Tablet
It is a Paracetamol 650mg Tablet by Arrowin Pharmaceuticals, indicated for the relief of fever and pain in adults. It is one of the most widely prescribed antipyretic and analgesic formulations in India, trusted by physicians across general practice, internal medicine and emergency care for its well-established efficacy, rapid onset and excellent tolerability profile.
Paracetamol works by inhibiting prostaglandin synthesis in the central nervous system and by acting on the hypothalamic heat-regulating centre to reduce elevated body temperature. Unlike NSAIDs, Paracetamol does not inhibit peripheral prostaglandin synthesis, which means it does not carry the gastrointestinal side effects associated with that drug class. This makes it the preferred analgesic and antipyretic in patients with gastric sensitivity, peptic ulcer disease or those who cannot tolerate conventional NSAIDs.
The 650mg strength of Temgrip-650 provides a higher therapeutic dose than the standard 500mg tablet, making it more appropriate for adults requiring effective control of moderate- to high-grade fever or significant pain. The higher dose also extends the duration of action, reducing the frequency of dosing required throughout the day and improving patient compliance.
Composition
Each tablet contains Paracetamol IP 650mg.
Therapeutic Class
Antipyretic and Analgesic.
Indications
Temgrip-650 is indicated for the management of fever, including high-grade fever, influenza-associated fever and post-vaccination fever. It is also prescribed for pain relief in conditions including headache, migraine, toothache, body ache, musculoskeletal pain and osteoarthritis. It is commonly used for symptomatic management of seasonal flu and cold-associated symptoms.
Dosage and Administration
The standard adult dose is one tablet of Temgrip-650 taken orally every 6 to 8 hours as needed. The maximum recommended dose of Paracetamol for adults is 4 grams per 24 hours across all sources combined. Temgrip-650 should be taken with or after food. Always follow the prescribing physician’s instructions on dose and duration. Do not exceed the recommended daily dose.
Packaging
10×15 blister (150 tablets per pack).
Are There Any Side Effects of Temgrip-650?
Paracetamol is one of the safest and most well-tolerated analgesics and antipyretics available when used at recommended doses. Side effects at therapeutic doses are rare. Some individuals may experience mild nausea or stomach discomfort, which typically resolves without discontinuation.
The most significant risk associated with Paracetamol is hepatotoxicity from overdose. Exceeding the maximum recommended daily dose of 4 grams in adults, particularly in patients with pre-existing liver disease or those consuming alcohol regularly, can cause serious liver damage. Physicians should advise patients to account for all sources of Paracetamol intake, including combination cold-and-flu products, before prescribing additional doses.
Temgrip-650 should be used with caution in patients with hepatic impairment, chronic alcoholism or severe renal impairment. It is contraindicated in patients with known hypersensitivity to Paracetamol.
FAQ Section
What is Temgrip-650 used for?
Temgrip-650 is a Paracetamol 650mg tablet used for relief from fever, headache, body ache, toothache, migraine, flu symptoms and musculoskeletal pain in adults. It is also prescribed for post-vaccination fever management.
Why is 650mg better than the standard 500mg Paracetamol tablet?
The 650mg dose provides a stronger therapeutic effect for moderate to high-grade fever and significant pain, and offers a longer duration of action compared to the 500mg strength. This means fewer doses are needed throughout the day, which improves treatment compliance in adults.
Is Temgrip-650 an NSAID?
No. Paracetamol is an antipyretic and analgesic, but is not classified as a non-steroidal anti-inflammatory drug. Unlike NSAIDs, it does not inhibit peripheral prostaglandin synthesis and therefore does not carry the gastrointestinal risks associated with that class. This makes it suitable for patients who cannot tolerate NSAIDs.
Can Temgrip-650 be taken on an empty stomach?
Yes, Paracetamol is generally well tolerated on an empty stomach. However, taking it with or after food is recommended to minimise any possibility of gastric discomfort, particularly with regular use.
Is Temgrip-650 available for PCD Pharma Franchise?
Yes. Temgrip-650 is available for PCD distribution with monopoly rights across territories. Contact Arrowin Pharmaceuticals to discuss franchise opportunities in your region.
